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By correcting the imbalance of the supply of serotonin. Evidence suggests an imbalance of serotonin, a chemical messenger in the brain that helps maintain mental balance. Lexapro blocks the re-absorption of serotonin by the first nerve cell. Lexapro is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors. Lexapro is taken orally, as often as indicated in the prescription of your doctor. As an anxiety medicine and they also appreciate that Lexapro is a small pill that is easy to swallow. Lexapro is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors. Lexapro works by increasing the available supply of serotonin.