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This medicine should not be taken within four hours of colestipol or cholestyramine, as these medicines may reduce the absorption of hydrochlorothiazide from the gut. Take Hydrochlorothiazide as directed, with meals, early in the day to avoid nocturia. Hydrochlorothiazide is often used to treat high blood pressure. As heart, liver, or kidney disease. Hydrochlorothiazide may increase the blood level of the medicine lithium, and this medicine is therefore not recommended for people taking lithium.
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